Back from stage 3 ovarian cancer, Stephanie Virgin is a mom and thriving professional

Cancer journey has turned survivor into an advocate for awareness.

Photo by Anna May Photography

Stephanie Virgin was 29 and hoping to start a family, so ovarian cancer was the last thing on her mind — even when she experienced textbook symptoms.

The Louisville native chalked up her back pain to the high heels she wore to her work in real estate. She thought the need to urinate frequently was from all the water she drank, and she blamed the cramping, bloating and irregular periods on going off birth control. And then there was the heartburn, decreased appetite and fatigue.

When she almost passed out one morning in September 2014, her husband, Greg, insisted she go to the doctor. Her physician pressed on her belly and felt what he thought was a large ovarian cyst. An ultrasound showed something more ominous.

“When you get told you have cancer, you black out. … I literally froze,” Stephanie said.

Stephanie did not fit any of the risk groups. She was young. The average age of diagnosis is 63.

Also, she had no family history of breast or ovarian cancer, didn’t smoke, wasn’t overweight, did not have endometriosis and never had taken fertility medications.

Stephanie’s surgeon found cancer on both ovaries, fallopian tubes, uterus, cervix, bladder, ureter, omentum and colon. Her diagnosis: stage 3 low-grade serous adenocarcinoma.

Stephanie went to see Lynn Parker, M.D., gynecologic oncologist with Norton Cancer Institute.

“Dr. Parker is big on research,” Stephanie said

The research showed patients who can tolerate an aggressive treatment (IV/IP chemotherapy) survive an additional 18 months on average.

“I felt like this was my best chance,” Stephanie said.

The inpatient chemotherapy was difficult. She was given Taxol intravenously, and the chemo drug cisplatin was injected directly into her abdomen, a procedure called intraperitoneal, or IP, chemotherapy.  The treatment caused the number of infection-fighting white blood cells called neutrophils to decrease to the point where Stephanie needed blood transfusions.

“That was tough,” she said. “Dr. Parker was always there to answer any question you had. When you talk to her, it’s like you’re her only patient. She doesn’t need to look at the chart to see who is this and what is this about.”

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After 5 years, still under surveillance

After five years, Stephanie is being monitored closely and taking medication because of a high recurrence rate for ovarian cancer.

Stephanie speaks to third-year medical students about her experience and does other outreach to spread the word about ovarian cancer, which strikes 1 in every 88 women.

“I had almost every symptom,” Stephanie said.

Those symptoms, however, are relatively easy to ignore or blame on something else.

“Ovarian cancer is called the silent killer or the cancer that whispers,” Stephanie said.

Stephanie belongs to Ovarian Awareness of Kentucky (OAK) and tries to use social media such as Facebook and Instagram to let women know about ovarian cancer, especially younger women who may not think they are at risk.

She also tries to mentor young survivors through an Ovarian Cancer Young Survivors Facebook page she started, which has more than 500 members.

Stephanie is back at work, running First Saturday Real Estate with her husband.

Ovarian cancer risk factors

Factors that may increase risk for ovarian cancer include:

  • Personal or family history of breast, ovarian or colon cancer. This includes close family members — mother, sister, aunt or grandmother — on either the mother’s or the father’s side.
  • Genetics. This includes having a family cancer syndrome from mutations in certain genes, such as BRCA1 and BRCA2.
  • Age. Most ovarian cancers occur after menopause, with half occurring in women over age 63.
  • Fertility/pregnancies. Risk is higher for women who have never given birth or have had trouble getting pregnant, as well as women who had their first full-term pregnancy after age 35.
  • Hormone replacement. Use of hormone replacement therapy after menopause.

Discuss all of your risk factors with your OB/GYN during your annual well-woman exam. Women with one or more risk factors should be vigilant about symptoms.

‘Whatever it takes for you to be a mommy’

Because she had a radical hysterectomy, Stephanie knew she couldn’t have children.

“For me one of the toughest things was the loss of my fertility. I went through a period of mourning,” Stephanie said. “I cried and told my husband, ‘We would have made such beautiful babies. My husband was amazing. He said, ‘We’re going to do whatever it takes for you to be a mommy.’”

Stephanie and Greg have since adopted biological brothers through the foster care system. The boys are now ages 7 and 3.

“We have two beautiful boys,” said Stephanie, who is passionate about her family and her work.

Stephanie said her cancer journey has changed her outlook. She now says yes to more experiences and risks, like starting her own business.

Signs and symptoms of ovarian cancer

Early stage ovarian cancer seldom causes symptoms. Advanced stage ovarian cancer may cause symptoms that are often mistaken for common benign symptoms.

Signs and symptoms of ovarian cancer may include:

  • Abdominal bloating or swelling
  • Quickly feeling full when eating
  • Weight loss
  • Discomfort in the pelvis area
  • Changes in bowel habits, such as constipation
  • A frequent need to urinate

Your doctor can review your family history with you. If you have relatives with ovarian cancer, you may want to meet with a genetic counselor to discuss testing for certain gene mutations that can increase your risk.


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