Heart and Vascular Clinical Trials

Norton Heart and Vascular Institute physicians are innovators in patient care. As principal investigators on numerous trials, our specialist physicians have access to ground-breaking treatments.

Learn more about participating in a clinical trial at Norton Healthcare.

Active clinical trials at Norton Heart & Vascular Institute include:

Acute Coronary Syndrome (ACS)

A Phase 3, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Efficacy and Safety of CSL112 in Subjects with Acute Coronary Syndrome

Chronic Heart Failure

A phase III randomised, double-blind trial to evaluate efficacy and safety of once daily empagliflozin 10 mg compared to placebo, in patients with chronic Heart Failure with preserved Ejection Fraction (HFpEF)

Congestive Heart Failure

Strategic MAnagement to Improve CRT Using Multi-Site Pacing Post Approval

Coronary Artery Disease

Randomized trial of COBRA PzF Stenting To Reduce Duration of Triple Therapy (COBRA?REDUCE)

Graft Procedure

Jostent GraftMaster Coronary Stent Graft & Delivery System for the treatement of free perforation, defined as free contrast extravasation into the pericardium, in native coronary vessels or saphenous vein bypass grafts

Heart Failure

Product Surveillance Registry / Site 10123001

Heart Failure

Care OptimizatioN through PatieNt and Hospital Engagement Clinical Trial for Heart Failure, CONNECT-HF trial

Lung Surgery

HUMANITARIAN USE DEVICE: The Spiration® Valve System Protocol# H060002

Clinical trials

Clinical Trials

Learn more about clinical trials at Norton Healthcare
(502) 629-3501

When the doctor becomes the patient

Gerald F. Sturgeon, M.D., has been a pediatrician in the Louisville community for 50 years and with Norton Children’s Medical Associates – Dupont since 2011. He recently found himself on the receiving end of patient […]

Read Full Story

Why you should care about these 8 risk factors for heart disease

We get bombarded by health news, research, tips and warnings every day. Eat this, don’t eat that. Do this, don’t do that. Sometimes there’s a lot of noise, and we miss the message. Here’s a […]

Read Full Story

Heart-healthy recipes: Low-fat pineapple slaw

Love coleslaw but wish for a version without so much mayo? Here’s a solution. This refreshing take on slaw boasts bold flavors, but stays light with the addition of sweet pineapple and light yogurt.  This […]

Read Full Story

Can stress cause a heart attack?

Your body’s fight or flight response is nature’s way of helping you cope with stressful situations. Faced with stress, your body will secrete adrenaline to amp up your breathing, heart rate and blood pressure — […]

Read Full Story

What is TAVR?

Transcatheter aortic valve replacement (TAVR) is an alternative to open-heart surgery to replace the aortic valve. Interventional cardiologists and cardiothoracic surgeons at Norton Heart & Vascular Institute team up to conduct a TAVR procedure. Performed [...]

Read Full Story
Related Stories

When the doctor becomes the patient

Gerald F. Sturgeon, M.D., has been a pediatrician in the Louisville community for 50 years and with Norton Children’s Medical Associates – Dupont since 2011. He recently found himself on the receiving end of patient […]

Read Full Story

Why you should care about these 8 risk factors for heart disease

We get bombarded by health news, research, tips and warnings every day. Eat this, don’t eat that. Do this, don’t do that. Sometimes there’s a lot of noise, and we miss the message. Here’s a […]

Read Full Story

Heart-healthy recipes: Low-fat pineapple slaw

Love coleslaw but wish for a version without so much mayo? Here’s a solution. This refreshing take on slaw boasts bold flavors, but stays light with the addition of sweet pineapple and light yogurt.  This […]

Read Full Story

Can stress cause a heart attack?

Your body’s fight or flight response is nature’s way of helping you cope with stressful situations. Faced with stress, your body will secrete adrenaline to amp up your breathing, heart rate and blood pressure — […]

Read Full Story

What is TAVR?

Transcatheter aortic valve replacement (TAVR) is an alternative to open-heart surgery to replace the aortic valve. Interventional cardiologists and cardiothoracic surgeons at Norton Heart & Vascular Institute team up to conduct a TAVR procedure. Performed [...]

Read Full Story

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