Heart and Vascular Institute Clinical Trials | Norton Healthcare Louisville, Ky.

Norton Heart & Vascular Institute Clinical Trials

Norton Heart and Vascular Institute physicians are innovators in patient care. As principal investigators on numerous trials, our specialist physicians have access to ground-breaking treatments.

Learn more about participating in a clinical trial at Norton Healthcare.

Active clinical trials at Norton Heart & Vascular Institute include:

Acute Coronary Syndrome (ACS)

A Phase 3, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Efficacy and Safety of CSL112 in Subjects with Acute Coronary Syndrome

Acute Decompensated Heart Failure (ADHF)

A multicenter, randomized, double-blind, double-dummy, parallel group, active controlled 8-week study to evaluate the effect of sacubitril/valsartan (LCZ696) versus valsartan on changes in NT-proBNP and safety and tolerability of in-hospital initiation of LCZ696 compared to […]

Chronic Heart Failure

A phase III randomised, double-blind trial to evaluate efficacy and safety of once daily empagliflozin 10 mg compared to placebo, in patients with chronic Heart Failure with preserved Ejection Fraction (HFpEF)

Graft Procedure

Jostent GraftMaster Coronary Stent Graft & Delivery System for the treatement of free perforation, defined as free contrast extravasation into the pericardium, in native coronary vessels or saphenous vein bypass grafts

Heart Failure

Product Surveillance Registry / Site 10123001

Heart Failure

Care Optimization through Patient and Hospital Engagement Clinical Trial for Heart Failure, CONNECT-HF trial

Lung Surgery

HUMANITARIAN USE DEVICE: The Spiration® Valve System Protocol# H060002

Clinical trials

Clinical Trials

Learn more about clinical trials at Norton Healthcare
(502) 629-3501

Some pregnancy complications can signal risk for heart disease after delivery

Pre-eclampsia and gestational hypertension are two common forms of high blood pressure during pregnancy. Once baby is born and blood pressure falls, many women move on with their busy lives. But these pregnancy complications are […]

Read Full Story

LaGrange man’s journey from heart failure to heart recovery

The last thing Keith Drury remembers from the day his heart stopped is driving to a job site near the Kentucky River. He doesn’t remember going into cardiac arrest, the CPR or the emergency helicopter […]

Read Full Story

Your how-to for a healthy heart diet

If you’re ready to get serious about adopting a healthy heart diet, you don’t need to deprive yourself, and you don’t need the latest fad. Eating wholesome foods is a simple lifestyle change that can […]

Read Full Story

When Marty Metcalfe woke up, it didn’t seem like a heart issue — but it was

The day that changed Marty Metcalfe’s life began when she awoke with a terrible headache and tightness in the artery on the right side of her neck. She chalked it up to the high stress […]

Read Full Story

Cardiac electrophysiologist has heart-care roots

You could say that for Sofya Kuznetsov, M.D., cardiology is in her blood. Her mother was a cardiologist in her native Russia. “I saw how grateful her patients were. Some of them became her lifelong […]

Read Full Story
Related Stories

Some pregnancy complications can signal risk for heart disease after delivery

Pre-eclampsia and gestational hypertension are two common forms of high blood pressure during pregnancy. Once baby is born and blood pressure falls, many women move on with their busy lives. But these pregnancy complications are […]

Read Full Story

LaGrange man’s journey from heart failure to heart recovery

The last thing Keith Drury remembers from the day his heart stopped is driving to a job site near the Kentucky River. He doesn’t remember going into cardiac arrest, the CPR or the emergency helicopter […]

Read Full Story

Your how-to for a healthy heart diet

If you’re ready to get serious about adopting a healthy heart diet, you don’t need to deprive yourself, and you don’t need the latest fad. Eating wholesome foods is a simple lifestyle change that can […]

Read Full Story

When Marty Metcalfe woke up, it didn’t seem like a heart issue — but it was

The day that changed Marty Metcalfe’s life began when she awoke with a terrible headache and tightness in the artery on the right side of her neck. She chalked it up to the high stress […]

Read Full Story

Cardiac electrophysiologist has heart-care roots

You could say that for Sofya Kuznetsov, M.D., cardiology is in her blood. Her mother was a cardiologist in her native Russia. “I saw how grateful her patients were. Some of them became her lifelong […]

Read Full Story

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