Heart and Vascular Institute Clinical Trials | Norton Healthcare Louisville, Ky.

Norton Heart & Vascular Institute Clinical Trials

Norton Heart and Vascular Institute physicians are innovators in patient care. As principal investigators on numerous trials, our specialist physicians have access to ground-breaking treatments.

Learn more about participating in a clinical trial at Norton Healthcare.

Active clinical trials at Norton Heart & Vascular Institute include:

Acute Coronary Syndrome (ACS)

A Phase 3, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Efficacy and Safety of CSL112 in Subjects with Acute Coronary Syndrome

Acute Decompensated Heart Failure (ADHF)

A multicenter, randomized, double-blind, double-dummy, parallel group, active controlled 8-week study to evaluate the effect of sacubitril/valsartan (LCZ696) versus valsartan on changes in NT-proBNP and safety and tolerability of in-hospital initiation of LCZ696 compared to […]

Acute Decompensated Heart Failure (ADHF)

Benefits of Microcor (uCorTM) in Ambulatory Decompensated Heart Failure

Atrial Arrhythmias

Tracking Results of Ablations to Combat AF Registry (Formerly the Maze IV Registry)

Chronic Obstructive Pulmonary Disease (COPD)

A Sham Controlled Prospective Randomized Clinical Trial of the RejuvenAir® System for the Treatment of Moderate to Severe Chronic Obstructive Pulmonary Disease with Chronic Bronchitis (SPRAY-CB)

Coronary Artery Disease

Prospective Randomized Trial of the Optimal Evaluation of Cardiac Symptoms and Revascularization

Graft Procedure

Jostent GraftMaster Coronary Stent Graft & Delivery System for the treatement of free perforation, defined as free contrast extravasation into the pericardium, in native coronary vessels or saphenous vein bypass grafts

Heart Failure

Care Optimization through Patient and Hospital Engagement Clinical Trial for Heart Failure, CONNECT-HF trial

Heart Failure

Product Surveillance Registry / Site 10123001

Lung Surgery

HUMANITARIAN USE DEVICE: The Spiration® Valve System Protocol# H060002

Major Adverse Cardiovascular Events (MACE)

SELECT – Semaglutide effects on cardiovascular outcomes in people with overweight or obesity

Total Hip Arthroplasty (THA)

Stopping fish oil supplementation prior to total hip replacement a randomized clinical trial

Clinical trials

Clinical Trials

Learn more about clinical trials at Norton Healthcare
(502) 629-3500

What is a calcium score?

A coronary calcium scan is a test for people who have no symptoms of heart disease but may be at borderline or intermediate risk for getting it. The test uses computed tomography (CT) to check for […]

Read Full Story

Why chest pain in women is different and shouldn’t be dismissed

Chest pain in women is often different from men’s typical experiences. Also known as angina, heart-related chest pain is the result of a decrease in blood flow to the heart. It can be difficult to [...]

Read Full Story

Innovative care to help make patients safer

When Arnold Belker, M.D., went for a magnetic resonance imaging (MRI) scan at Norton Brownsboro Hospital recently, he became a medical pioneer of sorts. His cardiac device had to be programmed into an MRI-safe mode […]

Read Full Story

Recipe: Corn and heirloom radish salad

This quick recipe comes together in about 25 minutes and keeps in the fridge for several days. This can be eaten alone or served on top of fresh salad greens as a unique salad topper […]

Read Full Story

What heart patients need to know about COVID-19

For a heart patient, avoiding infection with COVID-19 and keeping in touch with your cardiologist can be critical. COVID-19 primarily attacks the lungs, but it can both directly and indirectly affect the heart as well. [...]

Read Full Story
Related Stories

What is a calcium score?

A coronary calcium scan is a test for people who have no symptoms of heart disease but may be at borderline or intermediate risk for getting it. The test uses computed tomography (CT) to check for […]

Read Full Story

Why chest pain in women is different and shouldn’t be dismissed

Chest pain in women is often different from men’s typical experiences. Also known as angina, heart-related chest pain is the result of a decrease in blood flow to the heart. It can be difficult to [...]

Read Full Story

Innovative care to help make patients safer

When Arnold Belker, M.D., went for a magnetic resonance imaging (MRI) scan at Norton Brownsboro Hospital recently, he became a medical pioneer of sorts. His cardiac device had to be programmed into an MRI-safe mode […]

Read Full Story

Recipe: Corn and heirloom radish salad

This quick recipe comes together in about 25 minutes and keeps in the fridge for several days. This can be eaten alone or served on top of fresh salad greens as a unique salad topper […]

Read Full Story

What heart patients need to know about COVID-19

For a heart patient, avoiding infection with COVID-19 and keeping in touch with your cardiologist can be critical. COVID-19 primarily attacks the lungs, but it can both directly and indirectly affect the heart as well. [...]

Read Full Story

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