ALS or Lou Gehrig’s Disease

Schedule an appointment online or call

Norton Neuroscience Institute is the leading provider of neurological care in Louisville and Southern Indiana, with specialists providing advanced care for patients with amyotrophic lateral sclerosis (ALS), often known as Lou Gehrig’s disease.

ALS is a progressive motor neuron disease affecting the nerve cells in the brain and spinal cord.

Progressive degeneration of the motor neurons causes them to die, and the brain loses its connection to muscles. The result is a lack of muscle control. This “disconnection” then causes the muscle to lose neuron nourishment and stimulation, resulting in muscle atrophy.

There is no cure for ALS, but care from a range of medical specialties focused on your case can extend functionality and survival.

Extending Functionality and Survival for ALS Patients

The Norton Healthcare ALS Multidisciplinary Clinic brings together specialized neurologists, respiratory therapists, dietitians, occupational therapists and other health professionals.

The ALS Multidisciplinary Clinic also helps patients with primary lateral sclerosis (PLS). Directed by Mark P. Bazant, M.D., neurologist with Norton Neuroscience Institute specializing in ALS, the clinic provides supportive care as well as medication.

The clinic provides solutions that can help with breathing and swallowing. The clinic also can help with simple or high-tech solutions to help ALS patients communicate.

Many patients are able to share quality time with their families and others with the clinic’s help.

What Is ALS?

With degeneration of the motor neurons that carry signals from the brain to the spinal cord and out to the muscles, the brain loses the ability to initiate movement. That means it becomes increasingly difficult to speak, eat, move and breathe.

Only about 5% to 10% of ALS cases are inherited. In the vast majority of cases, the cause is unknown. ALS affects about five out of every 100,000 people worldwide.

ALS usually affects people between the ages of 40 and 70. ALS recognition increased significantly after the disease shortened New York Yankees great Lou Gehrig’s career in 1939.

More recently, physicist Stephen Hawking lived more than 50 years after his ALS diagnosis, dying in 2018 at age 76.

ALS Diagnosis

The board-certified and fellowship-trained specialists at Norton Neuroscience Institute have the experience to diagnose ALS.

There is no single test or procedure to diagnose ALS. Experienced specialists, however can rule out other diseases that mimic ALS to make an accurate diagnosis.

A physical exam usually includes an extensive strength and endurance exam. A patient with ALS may have an abnormal gait. Reflexes are often abnormal in that they will be increased at the joint and reduced in the gag reflex. Some patients may have trouble controlling episodes of crying or laughing, often called “emotional incontinence.”

Your physician will conduct diagnostic tests to pinpoint your condition. Tests may include:

  • Neurological exam
  • Electromyography (EMG) and nerve conduction velocity (NCV)
  • Blood and urine studies
  • Spinal tap
  • X-rays, including magnetic resonance imaging (MRI)
  • Myelogram of the cervical spine
  • Muscle and/or nerve biopsy

Leading the Region in Neurological Care

National Association of Epilepsy Centers Level 4 seal
  • Breakthrough essential tremor and Parkinson’s disease treatment: We are the first health care system in Kentucky  to offer high-frequency focused ultrasound to treat these conditions without any incisions.
  • Slowing the progression of Alzheimer’s disease: We are the first health care system in Kentucky to offer lecanemab and a leader nationally in the application of this cutting-edge drug.
  • Highest level of stroke care
    • Four Norton Healthcare adult-service hospitals are DNV-certified for stroke care, reflecting the highest standards in rapid treatment and outcomes.
    • Four adult-service hospitals have earned American Heart Association Get With the Guidelines awards for exceptional stroke care, including multiple Gold Plus and Honor Roll designations.
  • More than 75 medical, surgical and research specialists collaborate to provide innovative treatment of brain, spine and nervous system conditions.
  • Norton Neuroscience Institute’s multiple sclerosis (MS) program has met the high standards to achieve Center for Comprehensive MS Care designation by the National Multiple Sclerosis Society.
  • The National Association of Epilepsy Centers has recognized Norton Neuroscience Institute Comprehensive Epilepsy Center as a Level 4 center, providing the highest level of medical and surgical evaluation and treatment for patients with complex epilepsy.
  • Norton Neuroscience Institute Resource Center navigators help educate patients and their families about new diagnoses, available treatments and ways to manage their disease.
  • Medicare, Medicaid and most major commercial insurance accepted; families with income equal to or less than 350% of the federal poverty level may be eligible for financial assistance.
  • Communicate with your provider, refill prescriptions, make appointments and more with the free Norton MyChart account.

Related Stories

Patients finding hope, life-changing care at the Norton Neuroscience Institute Adult Neurodevelopmental Program
New adaptive dance class brings hope and healing to those with Parkinson’s disease and other movement disorders
MS fatigue or am I just tired?
Norton Healthcare nationally recognized for commitment to providing high-quality cardiovascular and stroke care