Bladder Cancer and Urothelial Cancer Clinical Trials

Norton Cancer Institute is at the forefront of cancer treatment research. As principal investigators on numerous trials, our specialist physicians have access to innovative treatments and numerous bladder cancer clinical trials.

Learn more about participating in a clinical trial at Norton Healthcare.

Active bladder cancer and urothelial cancer clinical trials include:

Bladder Cancer

A Phase 3 Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Subjects with Advanced Urothelial Cancer and Selected FGFR Gene Aberrations

Muscle Invasive Bladder Cancer (MIBC)

A Phase III, Randomized, Open-Label, Multi-Center, Global Study to Determine the Efficacy and Safety of Durvalumab in Combination with Gemcitabine+Cisplatin for Neoadjuvant Treatment Followed by Durvalumab Alone for Adjuvant Treatment in Patients with Muscle-Invasive Bladder […]

Urothelial Cancer

Retrospective Observational Study to Assess the Efficacy of Anti-PD-(L)1 Treatment in Subjects with Fibroblast Growth Factor Receptor Aberrations

Urothelial Cancer

A Phase 1b-2 Study to Evaluate Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Erdafitinib plus JNJ-63723283, an Anti-PD-1 Monoclonal Antibody, in Subjects with Metastatic or Surgically Unresectable Urothelial Cancer with Selected FGFR Gene Alterations

Urothelial Cancer

A Phase III, Randomized, Open Label, Controlled, Multi-Center, Global Study of First-Line Durvalumab in Combination with Standard of Care Chemotherapy and Durvalumab in Combination with Tremelimumab and Standard of Care Chemotherapy Versus Standard of Care […]

Urothelial Cancer

A Phase II Open Label, Study of IMMU-132 in Metastatic Urothelial Cancer after Failure of Platinum-Based Regimen or Anti-PD-1/ PD-L1 Based Immunotherapy

Urothelial Cancer

A single-arm, open-label, multicenter study of enfortumab vedotin (ASG-22CE) for treatment of patients with locally advanced or metastatic urothelial cancer who previously received immune checkpoint inhibitor (CPI) therapy

Urothelial Carcinoma

A PHASE III, MULTICENTER, RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND STUDY OF ATEZOLIZUMAB (ANTI?PD-L1 ANTIBODY) IN COMBINATION WITH GEMCITABINE/CARBOPLATIN VERSUS GEMCITABINE/CARBOPLATIN ALONE IN PATIENTS WITH UNTREATED LOCALLY ADVANCED OR METASTATIC UROTHELIAL CARCINOMA WHO ARE INELIGIBLE FOR CISPLATIN-BASED THERAPY

Urothelial Carcinoma

A Phase Ib/II Open Label, Multicenter, Randomized Umbrella Study Evaluating The Efficacy And Safety Of Multiple Immunotherapy-Based Treatment Combinations In Patients With Locally Advanced Or Metastatic Urothelial Carcinoma After Failure With Platinum-Containing Chemotherapy (MORPHEUS-mUC)

Urothelial Carcinoma

A Phase 2 Study of Sitravatinib in Combination with Nivolumab in Patients with Advanced or Metastatic Urothelial Carcinoma

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Clinical trials

Clinical Trials

Learn more about clinical trials at Norton Healthcare
(502) 629-3501

NYU Study Links Vaping to Lung CancerStudy shows vaping nicotine could cause cancer

New research shows vaping’s dangers may extend beyond the recent wave of deaths from pulmonary disease, as vaping also may increase cancer risk. The first study found nearly 25% of mice developed lung cancer after […]

Read Full Story

How to quit smoking: Make a plan

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Art therapist’s breast cancer journey fuels passion to help others with the disease

While Leigh Galloway undergoes her last chemotherapy treatment before a double mastectomy, she and Laura Chamberlin are engrossed in a watercolor. Like she does often with Laura, an expressive art therapist with Norton Cancer Institute […]

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Pathology lab provides expertise in cancer and other conditions

Patients don’t see pathologists, but these physicians can make all the difference when it comes to diagnosing and treating cancer and other conditions, said Alvin W. Martin, M.D., medical director for Norton Healthcare’s CPA Lab. [...]

Read Full Story

Bringing new gynecologic cancer treatments and caring for patients like family

After working as an obstetrician/gynecologist for five years, Charles B. Palmer, D.O., was drawn to patients needing complex care. He decided to become a gynecologic oncologist, diagnosing and treating cancers in women’s reproductive organs. “The [...]

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Related Stories

NYU Study Links Vaping to Lung CancerStudy shows vaping nicotine could cause cancer

New research shows vaping’s dangers may extend beyond the recent wave of deaths from pulmonary disease, as vaping also may increase cancer risk. The first study found nearly 25% of mice developed lung cancer after […]

Read Full Story

How to quit smoking: Make a plan

You’ve made the decision to quit smoking, now what? Don’t try to do it right away. You need to make a plan and let those closest to you know you have decided to quit. Accept […]

Read Full Story

Art therapist’s breast cancer journey fuels passion to help others with the disease

While Leigh Galloway undergoes her last chemotherapy treatment before a double mastectomy, she and Laura Chamberlin are engrossed in a watercolor. Like she does often with Laura, an expressive art therapist with Norton Cancer Institute […]

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Pathology lab provides expertise in cancer and other conditions

Patients don’t see pathologists, but these physicians can make all the difference when it comes to diagnosing and treating cancer and other conditions, said Alvin W. Martin, M.D., medical director for Norton Healthcare’s CPA Lab. [...]

Read Full Story

Bringing new gynecologic cancer treatments and caring for patients like family

After working as an obstetrician/gynecologist for five years, Charles B. Palmer, D.O., was drawn to patients needing complex care. He decided to become a gynecologic oncologist, diagnosing and treating cancers in women’s reproductive organs. “The [...]

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