Leukemia Clinical Trials | Norton Healthcare Louisville, Ky.

Leukemia Clinical Trials

Norton Cancer Institute is at the forefront of cancer treatment research. As principal investigators on numerous trials, our specialist physicians have access to innovative treatments.

Learn more about participating in a clinical trial at Norton Healthcare.

Leukemia

A Multi-Center, Open-Label, Study to Evaluate the Safety and Efficacy of Ublituximab (TG-1101) in Combination with TGR-1202 for Patients Previously Enrolled in Protocol UTX-TGR-304

Leukemia

A Randomized, Multicenter, Open-Label, Phase 3 Study to Compare the Efficacy and Safety of Acalabrutinib (ACP-196) in Combination with Venetoclax with and without Obinutuzumab Compared to Investigator’s Choice of Chemoimmunotherapy in Subjects with Previously Untreated […]

Leukemia

Extended treatment protocol for subjects continuing to benefit from Ibrutinib after completion of Ibrutinib (PCI-32965) clinical trials.

Leukemia

Phase III Multicenter Open-Label Randomized Trial to Evaluate Efficacy and Safety of CPI-613 in Combination with High Dose Cytarabine and Mitoxantrone (CHAM) Compared to High Dose Cytarabine and Mitoxantrone (HAM) in Older Patients (≥ 60 […]

Leukemia

Tagraxofusp (SL-401) in Patients with Chronic Myelomonocytic Leukemia (CMML) or Myelofibrosis (MF)

Leukemia

ULTRA-V: Phase 2 Study to Assess the Efficacy and Safety of Ublituximab in Combination with Umbralisib and Venetoclax (U2-V) in Subjects with Chronic Lymphocytic Leukemia (CLL)

Leukemia

An Open-label, Multicenter, Phase 1b Study of JNJ-74494550 (Cusatuzumab; Anti-CD70 Monoclonal Antibody) in Combination with Background Therapy for the Treatment of Subjects with Acute Myeloid Leukemia

Leukemia

A Phase 1 Study of Safety, Pharmacokinetics, and Preliminary Activity of TAS1440, as a Single Agent and in Combination with All-Trans Retinoic Acid (ATRA) in Subjects with Relapsed or Refractory (r/r) Acute Myeloid Leukemia (AML)

Leukemia

A Randomized, Open-label, Controlled, Phase 2 Study of Pevonedistat, Venetoclax, and Azacitidine Versus Venetoclax Plus Azacitidine in Adults With Newly Diagnosed Acute Myeloid Leukemia Who Are Unfit for Intensive Chemotherapy

Leukemia

Randomized, Open-label, 2-Arm, Multicenter, Phase 3 Study of Venetoclax and Azacitidine Versus Best Supportive Care as Maintenance Therapy for Patients with Acute Myeloid Leukemia in First Remission After Conventional Chemotherapy (VIALE-M)

Leukemia

A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of dociparstat sodium in combination with standard chemotherapy for the treatment of newly-diagnosed acute myeloid leukemia

Leukemia

A Phase 3, Randomized, Double-blind, Active-Control Study of CPI-0610 and Ruxolitinib vs. Placebo and Ruxolitinib in JAKi Treatment Naive MF Patients

Leukemia

A Phase 1 Study of Safety, Pharmacokinetics and Preliminary Activity of TAS1553 in Subjects with Relapsed or Refractory (R/R) Acute Myeloid Leukemia (AML) and Other Myeloid Neoplasms

Leukemia

Phase Ib Study Evaluating the Safety and Efficacy of IBI188 in Combination with Azacitidine in Subjects with Newly Diagnosed Higher Risk Myelodysplastic Syndrome (MDS)

Leukemia

A Phase I/II open label study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and preliminary clinical efficacy of ONO-7475 in patients with acute leukemias or myelodysplastic syndromes

Leukemia

TWT-202 – Phase 2 Open-Label, Multicenter, Dose Optimization Clinical Study of the Safety, Tolerability, and Pharmacokinetic and Pharmacodynamic Profiles of CFI-400945 as a single agent or in Combination with Azacitidine or Decitabine in Patients with […]

Leukemia

A Phase 1b Dose Escalation Study of Lemzoparlimab in Combination with Azacitidine and/or Venetoclax in Subjects with Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

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Clinical trials

Clinical Trials

Learn more about clinical trials at Norton Healthcare
(502) 629-3500

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CAR-T cell therapy takes advantage of the body’s immune system to fight off cancer, much like it does already to kick the common cold and other types of illness. Our bodies don’t always fight off […]

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Ultraviolet light, specifically, narrowband UVB light, can reduce skin inflammation, especially as a treatment for eczema and psoriasis. A Louisville-area dermatologist is using this therapy as a treatment for cutaneous T-cell lymphoma, a blood cell […]

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In sickness and in health

The lump on Lonnie Gardner’s left arm looked innocuous. Maybe an insect bite, he reasoned. For weeks in 2014, the human resources professional went about his business, unconcerned. But the lump got larger and caught […]

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Why does a blood cancer start in the skin? Lymphomas are cancers of the immune system, which generally arise in lymph nodes and other lymphatic tissue.  The immune system consists of white blood cells, the […]

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When Brenda Montgomery enrolled in a clinical trial at Norton Cancer Institute in February 2016, she hoped the new drug being researched would trounce the cancer she had battled for nine years. She also hoped […]

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Related Stories

CAR-T cell therapy triggers the body’s own defenses to fight cancer

CAR-T cell therapy takes advantage of the body’s immune system to fight off cancer, much like it does already to kick the common cold and other types of illness. Our bodies don’t always fight off […]

Read Full Story

UVB light as a treatment for cutaneous lymphoma

Ultraviolet light, specifically, narrowband UVB light, can reduce skin inflammation, especially as a treatment for eczema and psoriasis. A Louisville-area dermatologist is using this therapy as a treatment for cutaneous T-cell lymphoma, a blood cell […]

Read Full Story

In sickness and in health

The lump on Lonnie Gardner’s left arm looked innocuous. Maybe an insect bite, he reasoned. For weeks in 2014, the human resources professional went about his business, unconcerned. But the lump got larger and caught […]

Read Full Story

Cutaneous lymphoma: Blood cancer that starts in the skin

Why does a blood cancer start in the skin? Lymphomas are cancers of the immune system, which generally arise in lymph nodes and other lymphatic tissue.  The immune system consists of white blood cells, the […]

Read Full Story

Cancer-free patient finds hope from clinical trial

When Brenda Montgomery enrolled in a clinical trial at Norton Cancer Institute in February 2016, she hoped the new drug being researched would trounce the cancer she had battled for nine years. She also hoped […]

Read Full Story

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