Breast Cancer Clinical Trials

Norton Cancer Institute is at the forefront of cancer treatment research. As principal investigators on numerous breast cancer clinical trials, our specialist physicians have access to innovative treatments.

Learn more about participating in a clinical trial at Norton Healthcare.

Active breast cancer clinical trials include:

Breast Cancer

A Phase III, Multicenter, Randomized, Open-label Trial to Evaluate Efficacy and Safety of Ribociclib with Endocrine Therapy as an Adjuvant Treatment in Patients with Hormone Receptor-Positive, HER2-Negative, Early Breast Cancer (New Adjuvant TriAl with Ribociclib […]

Breast Cancer

A phase I/II dose escalation and expansion study to investigate the safety, pharmacokinetics, pharmacodynamics and clinical activity of GSK525762 in combination with fulvestrant in subjects with hormone receptor-positive/HER2-negative (HR+/HER2-) advanced or metastatic breast cancer

Lung Cancer/ Breast Cancer

A Phase 1 Study to evaluate the safety, pharmacokinetics, and pharmacodynamics of escalating doses and treatment intensification of a vaccine-based immunotherapy Regimen-2 (VBIR-2) (PF-06936308) for advanced non-small cell lung cancer and metastatic triple-negative breast cancer

Cancer

A Phase 1b, Multicenter, Two-Part, Open-Label Study of DS-8201a, an Anti-Human Epidermal Growth Factor Receptor-2 (HER2)-Antibody Drug Conjugate (ADC), in Combination with Nivolumab, an anti-PD-1 antibody, for Subjects with HER2-expressing Advanced Breast and Urothelial Cancer

Metastatic Breast Cancer

A PHASE 3, MULTICENTER, RANDOMIZED, OPEN-LABEL, ACTIVE-CONTROLLED STUDY OF TRASTUZUMAB DERUXTECAN (DS-8201A,), AN ANTI-HER2-ANTIBODY DRUG CONJUGATE, VERSUS ADO-TRASTUZUMAB EMTANSINE (T-DM1) FOR HER2-POSITIVE, UNRESECTABLE AND/OR METASTATIC BREAST CANCER SUBJECTS PREVIOUSLY TREATED WITH TRASTUZUMAB AND TAXANE

Metastatic Breast Cancer

A PHASE 3, MULTICENTER, RANDOMIZED, OPEN-LABEL, ACTIVE-CONTROLLED STUDY OF TRASTUZUMAB DERUXTECAN (DS–8201A), AN ANTI-HER2-ANTIBODY DRUG CONJUGATE, VERSUS TREATMENT OF INVESTIGATOR’S CHOICE FOR HER2-POSITIVE, UNRESECTABLE AND/OR METASTATIC BREAST CANCER SUBJECTS PREVIOUSLY TREATED WITH T-DM1

Breast Cancer

Elacestrant Monotherapy Vs. Standard Of Care For The Treatment Of Patients With Er+/Her2- Advanced Breast Cancer Following Cdk4/6 Inhibitor Therapy: A Phase 3 Randomized, Open-Label, Active-Controlled, Multicenter Trial (EMERALD)

Breast Cancer

A Phase II, Open Label, Randomised, Multi-centre Study to Assess the Safety and Efficacy of Agents Targeting DNA Damage Repair in Combination with Olaparib versus Olaparib Monotherapy in the Treatment of Metastatic Triple Negative Breast […]

Breast Cancer

A Randomized, Double-Blind, Phase III Clinical Trial of Neoadjuvant Chemotherapy with Atezolizumab or Placebo in Patients with Triple-Negative Breast Cancer Followed by Adjuvant Continuation of Atezolizumab or Placebo

Education

Effects of a Smartphone App on Compliance and Function in Patients with Breast Cancer

Solid Tumors

A Phase 2/3, Multicenter, Randomized, Double Blind, Study to Evaluate Duration of Severe Neutropenia with Plinabulin Versus Pegfilgrastim in Patients with Solid Tumors Receiving Docetaxel Myelosuppressive Chemotherapy

Breast Cancer

NRG-BR003: A Randomized Phase III Trial of Adjuvant Therapy Comparing Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel with or without Carboplatin for Node-Positive or High-Risk Node-Negative Triple-Negative Invasive Breast Cancer

Breast Cancer

A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After […]

Cancer – 4673

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Clinical trials

Clinical Trials

Learn more about clinical trials at Norton Healthcare
(502) 629-3501

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Art therapist’s breast cancer journey fuels passion to help others with the disease

While Leigh Galloway undergoes her last chemotherapy treatment before a double mastectomy, she and Laura Chamberlin are engrossed in a watercolor. Like she does often with Laura, an expressive art therapist with Norton Cancer Institute […]

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Pathology lab provides expertise in cancer and other conditions

Patients don’t see pathologists, but these physicians can make all the difference when it comes to diagnosing and treating cancer and other conditions, said Alvin W. Martin, M.D., medical director for Norton Healthcare’s CPA Lab. [...]

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After working as an obstetrician/gynecologist for five years, Charles B. Palmer, D.O., was drawn to patients needing complex care. He decided to become a gynecologic oncologist, diagnosing and treating cancers in women’s reproductive organs. “The [...]

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Bike to Beat Cancer raises more than $525,000 for Norton Cancer Institute

Riders, donors and everyone who participated in the 11th annual Bike to Beat Cancer raised more than $525,000 for Norton Cancer Institute. The Saturday, Sept. 14, ride began and ended at Norton Cancer Institute – […]

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Read Full Story

Art therapist’s breast cancer journey fuels passion to help others with the disease

While Leigh Galloway undergoes her last chemotherapy treatment before a double mastectomy, she and Laura Chamberlin are engrossed in a watercolor. Like she does often with Laura, an expressive art therapist with Norton Cancer Institute […]

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Patients don’t see pathologists, but these physicians can make all the difference when it comes to diagnosing and treating cancer and other conditions, said Alvin W. Martin, M.D., medical director for Norton Healthcare’s CPA Lab. [...]

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