Liver Cancer

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Norton Cancer Institute provides comprehensive care for patients with liver cancer affecting the liver and pancreas, including primary and metastatic cancers as well as suspicious liver masses.

Specialties include:

  • Metastatic colorectal cancer
  • Hepatocellular carcinoma (HCC), the most common type of liver cancer
  • Cholangiocarcinoma (cancer in the tubes that carry digestive fluid through the liver)
  • Gallbladder carcinoma
  • Other metastatic diseases to the liver: neuroendocrine (carcinoid), breast, lung, esophageal

By combining the expertise of multiple specialists in one setting, a single referral offers you and your loved ones a full range of advanced liver cancer therapies. Extensive cancer support services are readily available from diagnosis through treatment and beyond, providing comfort wherever you are in the journey. Include access to leading national cancer clinical trials in Louisville, and you’ll find everything you need to take on your condition with confidence.

Learn more about liver cancer below, including signs, symptoms and risk factors to know. To make an appointment, or for more information, call (502) 629-4440.

Liver Cancer Risk Factors

The common component to the majority of liver cancer risk factors is chronic irritation, which causes liver cells to divide more quickly.

Specific risk factors for developing liver cancer include:

  • Chronic hepatitis
  • Cirrhosis
  • Alcoholism
  • Irritants to the liver such as:
    • Polyvinyl chloride (PVC)
    • Thorotrast
    • Radiation exposure
    • Liver flukes (linked with bile duct cancer in China)

Preventing Liver Cancer

To help prevent liver cancer, experts advise limiting alcohol consumption, as well as exposure to the hepatitis virus. Vaccines for hepatitis B are available and usually recommended for children and individuals considered at high risk for contracting the disease. A healthy diet and regular exercise can also help lower your risk for developing liver cancer.

Liver Cancer Signs and Symptoms

Most liver cancers do not cause symptoms until late stages, but sometimes they do occur earlier. Signs and symptoms include:

  • Unexplained weight loss
  • Lack of appetite
  • Feeling very full after a small meal
  • Ongoing stomach pain
  • Swelling in the stomach area
  • Yellow-green coloration of the skin and eyes, known as jaundice
  • Chronic hepatitis or cirrhosis that worsens
  • Liver enlargement or a mass that can be felt in the liver area
Gastrointestinal Cancer Team

Norton Cancer Institute

Regional Leader in Cancer Care

  • First in the world to treat a patient with a novel combination therapy for newly diagnosed acute leukemia
  • First in the world to treat a solid tumor patient with ONC-841, a novel immunotherapy drug targeting the SIGLEC-10 immune checkpoint molecule
  • Access to over 170 clinical trials, offering local patients the same leading-edge options available at top national centers
  • Nationally recognized center for early-phase research, with 23 active Phase 1 clinical trials underway
  • Patients from 20-plus U.S. states and two foreign countries have chosen Norton Cancer Institute for innovative cancer care
  • Only in Kentucky: Home to a state-of-the-art Norton Cancer Institute Genomics Lab, with support from the Norton Healthcare Foundation and Steven Vanover Foundation, enabling highly precise, genetically targeted cancer therapies
  • Gamma Tile Center of Excellence, as well as a two-time Novalis certification for setting the standard for stereotactic radiation
  • Subspecialized, board-certified oncologists leading cancer research and treatment advancements
  • Same-day or next-day appointments for newly diagnosed patients, plus multiple locations and valet parking to facilitate access to care
  • Multidisciplinary clinics to provide same-day, same-location access to multiple specialists for more convenient, coordinated care
  • Fully accredited by the American College of Surgeons Commission on Cancer, the National Accreditation Program for Breast Centers and the American College of Radiology

Care Designed With You in Mind

  • Comprehensive patient support, with five Norton Cancer Institute Resource Centers throughout Louisville and Southern Indiana, a patient navigator program, Norton Cancer Institute Behavioral Oncology Program, Norton Palliative Care Program, classes and events, art and music therapy, genetic counseling, nutrition services, financial counseling, pastoral care, and more
  • Medicare, Medicaid and most major insurances accepted, ensuring broad access to care
  • Specialty pharmacy services offer timely, accurate prescriptions with direct pharmacist-provider collaboration
  • 24/7 access to care tools via Norton MyChart — message providers, manage appointments, refill prescriptions and more
  • The Norton Healthcare Foundation, the philanthropic arm of Norton Healthcare’s not-for-profit adult-care services, continuously supporting the purchase of new equipment, programs, education and funding of research to ensure our patients stay up to date with medical advances and technology

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